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  • Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo

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Basic and translational research
Extended report
Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo

Authors

  • Suzanne Eldridge Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK PubMed articlesGoogle scholar articles
  • Giovanna Nalesso Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK PubMed articlesGoogle scholar articles
  • Habib Ismail Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK PubMed articlesGoogle scholar articles
  • Karin Vicente-Greco Department of Surgical Research, NPIMR Y3, Harrow, UK PubMed articlesGoogle scholar articles
  • Panos Kabouridis The Francis Crick Institute (Mill Hill Laboratory), The Ridgeway, London, UK PubMed articlesGoogle scholar articles
  • Manoj Ramachandran Department of Trauma and Orthopaedic Surgery, Royal London Hospital, London, UK PubMed articlesGoogle scholar articles
  • Andreas Niemeier Department of Orthopaedics and IBMII: Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany PubMed articlesGoogle scholar articles
  • Joachim Herz Department of Molecular Genetics, Center for Translational Neurodegeneration Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA PubMed articlesGoogle scholar articles
  • Costantino Pitzalis Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK PubMed articlesGoogle scholar articles
  • Mauro Perretti Centre for Biochemical Pharmacology, William Harvey Research Institute, London, UK PubMed articlesGoogle scholar articles
  • Francesco Dell'Accio Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK PubMed articlesGoogle scholar articles
  1. Correspondence to Suzanne Eldridge, Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK; s.e.eldridge{at}qmul.ac.uk
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Citation

Eldridge S, Nalesso G, Ismail H, et al
Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo
Annals of the Rheumatic Diseases 2016;75:1228-1235.

Publication history

  • Received January 16, 2015
  • Revised May 14, 2015
  • Accepted July 14, 2015
  • First published August 19, 2015.
Online issue publication 
October 31, 2019

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/