Table of contents

Clinical and epidemiological research

• Extended report:

  Effect of denosumab on Japanese patients with rheumatoid arthritis: a dose–response study of AMG 162 (Denosumab) in patients with RheumatoId arthritis on methotrexate to Validate inhibitory effect on bone Erosion (DRIVE)—a 12-month, multicentre, randomised, double-blind, placebo-controlled, phase II clinical trial

  (19 November, 2015)

  Tsutomu Takeuchi, Yoshiya Tanaka, Naoki Ishiguro, Hisashi Yamanaka, Toshiyuki Yoneda, Takeshi Ohira, Naoki Okubo, Harry K Genant, Désirée van der Heijde
• Extended report: Preliminary definitions of ‘flare’ in axial spondyloarthritis, based on pain, BASDAI and ASDAS-CRP: an ASAS initiative (4 February, 2016) Free

  Laure Gossec, Agnès Portier, Robert Landewé, Adrien Etcheto, Victoria Navarro-Compán, Féline Kroon, Désirée van der Heijde, Maxime Dougados
• Extended report: Occupational exposure to textile dust increases the risk of rheumatoid arthritis: results from a Malaysian population-based case–control study (17 December, 2015)

  Chun Lai Too, Nor Asiah Muhamad, Anna Ilar, Leonid Padyukov, Lars Alfredsson, Lars Klareskog, Shahnaz Murad, Camilla Bengtsson, MyEIRA Study Group
• Extended report: The comparative effectiveness of oral versus subcutaneous methotrexate for the treatment of early rheumatoid arthritis (15 May, 2015)

  Glen S Hazlewood, J Carter Thorne, Janet E Pope, Daming Lin, Diane Tin, Gilles Boire, Boulos Haraoui, Carol A Hitchon, Edward C Keystone, Shahin Jamal, Vivian P Bykerk
• Extended report: Efficacy of sildenafil on ischaemic digital ulcer healing in systemic sclerosis: the placebo-controlled SEDUCE study (20 May, 2015)

  Eric Hachulla, Pierre-Yves Hatron, Patrick Carpentier, Christian Agard, Emmanuel Chatelus, Patrick Jego, Luc Mouthon, Viviane Queyrel, Anne-Laure Fauchais, Ulrique Michon-Pasturel, Roland Jaussaud, Alexis Mathian, Brigitte Granel, Elisabeth Diot, Dominique Farge-Bancel, Arsène Mekinian, Jérôme Avouac, Hélène Desmurs-Clavel, Pierre Clerson
• Extended report: Prevalence of comorbidities and evaluation of their screening in spondyloarthritis: results of the international cross-sectional ASAS-COMOSPA study (21 October, 2015)

  Anna Moltó, Adrien Etcheto, Désirée van der Heijde, Robert Landewé, Filip van den Bosch, Wilson Bautista Molano, Ruben Burgos-Vargas, Peter P Cheung, Eduardo Collantes-Estevez, Atul Deodhar, Bassel El-Zorkany, Shandor Erdes, Jieruo Gu, Najia Hajjaj-Hassouni, Uta Kiltz, Tae-Hwan Kim, Mitsumasa Kishimoto, Shue-Fen Luo, Pedro M Machado, Walter P Maksymowych, José Maldonado-Cocco, Helena Marzo-Ortega, Carlo-Maurizio Montecucco, Salih Ozgoçmen, Floris van Gaalen, Maxime Dougados
• Extended report: Comparing the effects of tofacitinib, methotrexate and the combination, on bone marrow oedema, synovitis and bone erosion in methotrexate-naive, early active rheumatoid arthritis: results of an exploratory randomised MRI study incorporating semiquantitative and quantitative techniques (25 January, 2016)

  Philip G Conaghan, Mikkel Østergaard, Michael A Bowes, Chunying Wu, Thomas Fuerst, Désirée van der Heijde, Fedra Irazoque-Palazuelos, Oscar Soto-Raices, Pawel Hrycaj, Zhiyong Xie, Richard Zhang, Bradley T Wyman, John D Bradley, Koshika Soma, Bethanie Wilkinson
• Extended report: Predictive validity of the ASAS classification criteria for axial and peripheral spondyloarthritis after follow-up in the ASAS cohort: a final analysis (10 February, 2016)

  Alexandre Sepriano, Robert Landewé, Désirée van der Heijde, Joachim Sieper, Nurullah Akkoc, Jan Brandt, Jürgen Braun, Eduardo Collantes-Estevez, Maxime Dougados, Oliver Fitzgerald, Feng Huang, Jieruo Gu, Yesim Kirazli, Walter P Maksymowych, Helena Marzo-Ortega, Ignazio Olivieri, Salih Ozgocmen, Euthalia Roussou, Salvatore Scarpato, Inge J Sørensen, Rafael Valle-Oñate, Filip Van den Bosch, Irene van der Horst-Bruinsma, Ulrich Weber, James Wei, Martin Rudwaleit
• Extended report: Targeting ultrasound remission in early rheumatoid arthritis: the results of the TaSER study, a randomised clinical trial (29 March, 2016)

  James Dale, Anne Stirling, Ruiqi Zhang, David Purves, Jonathan Foley, Martin Sambrook, Philip G Conaghan, Désirée van der Heijde, Alex McConnachie, Iain B McInnes, Duncan Porter
• Extended report: Development and initial validation of international severity scoring system for familial Mediterranean fever (ISSF) (28 January, 2016)

  Erkan Demirkaya, Cengizhan Acikel, Philip Hashkes, Marco Gattorno, Ahmet Gul, Huri Ozdogan, Turker Turker, Omer Karadag, Avi Livneh, Eldad Ben-Chetrit, Seza Ozen, FMF Arthritis Vasculitis and Orphan disease Research in pediatric rheumatology (FAVOR)
• Extended report: Efficacy and safety of the oral Janus kinase inhibitor peficitinib (ASP015K) monotherapy in patients with moderate to severe rheumatoid arthritis in Japan: a 12-week, randomised, double-blind, placebo-controlled phase IIb study (15 December, 2015)

  Tsutomu Takeuchi, Yoshiya Tanaka, Manabu Iwasaki, Hiroaki Ishikura, Satoshi Saeki, Yuichiro Kaneko
• Extended report: Apremilast, an oral phosphodiesterase 4 inhibitor, in patients with psoriatic arthritis and current skin involvement: a phase III, randomised, controlled trial (PALACE 3) (20 January, 2016)

  Christopher J Edwards, Francisco J Blanco, Jeffrey Crowley, Charles A Birbara, Janusz Jaworski, Jacob Aelion, Randall M Stevens, Adele Vessey, Xiaojiang Zhan, Paul Bird
• Extended report: Lesinurad in combination with allopurinol: results of a phase 2, randomised, double-blind study in patients with gout with an inadequate response to allopurinol (7 January, 2016)

  Fernando Perez-Ruiz, John S Sundy, Jeffrey N Miner, Matthew Cravets, Chris Storgard
• Extended report: Tocilizumab in early progressive rheumatoid arthritis: FUNCTION, a randomised controlled trial (28 October, 2015)

  Gerd R Burmester, William F Rigby, Ronald F van Vollenhoven, Jonathan Kay, Andrea Rubbert-Roth, Ariella Kelman, Sophie Dimonaco, Nina Mitchell
• Extended report: The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort (18 May, 2015)

  Jaime Guzman, Kiem Oen, Adam M Huber, Karen Watanabe Duffy, Gilles Boire, Natalie Shiff, Roberta A Berard, Deborah M Levy, Elizabeth Stringer, Rosie Scuccimarri, Kimberly Morishita, Nicole Johnson, David A Cabral, Alan M Rosenberg, Maggie Larché, Paul Dancey, Ross E Petty, Ronald M Laxer, Earl Silverman, Paivi Miettunen, Anne-Laure Chetaille, Elie Haddad, Kristin Houghton, Lynn Spiegel, Stuart E Turvey, Heinrike Schmeling, Bianca Lang, Janet Ellsworth, Suzanne E Ramsey, Alessandra Bruns, Johannes Roth, Sarah Campillo, Susanne Benseler, Gaëlle Chédeville, Rayfel Schneider, Shirley M L Tse, Roxana Bolaria, Katherine Gross, Brian Feldman, Debbie Feldman, Bonnie Cameron, Roman Jurencak, Jean Dorval, Claire LeBlanc, Claire St. Cyr, Michele Gibbon, Rae S M Yeung, Ciarán M Duffy, Lori B Tucker
• Extended report: Identification of novel antiacetylated vimentin antibodies in patients with early inflammatory arthritis (9 July, 2015)

  Maria Juarez, Holger Bang, Friederike Hammar, Ulf Reimer, Bernard Dyke, Ilfita Sahbudin, Christopher D Buckley, Benjamin Fisher, Andrew Filer, Karim Raza
• Extended report: Predictive risk factors of serious infections in patients with rheumatoid arthritis treated with abatacept in common practice: results from the Orencia and Rheumatoid Arthritis (ORA) registry (5 June, 2015)

  J H Salmon, J E Gottenberg, P Ravaud, A Cantagrel, B Combe, R M Flipo, T Schaeverbeke, E Houvenagel, P Gaudin, D Loeuille, S Rist, M Dougados, J Sibilia, X Le Loët, O Meyer, E Solau-Gervais, C Marcelli, T Bardin, I Pane, G Baron, E Perrodeau, X Mariette
• Extended report: Validity of early MRI structural damage end points and potential impact on clinical trial design in rheumatoid arthritis (19 June, 2015)

  Joshua F Baker, Philip G Conaghan, Paul Emery, Daniel G Baker, Mikkel Østergaard
• Extended report: Does a family history of RA influence the clinical presentation and treatment response in RA? (19 June, 2015)

  Thomas Frisell, Saedis Saevarsdottir, Johan Askling
• Extended report: Effects of needs-based patient education on self-efficacy and health outcomes in people with rheumatoid arthritis: a multicentre, single blind, randomised controlled trial (10 July, 2015)

  M Ndosi, D Johnson, T Young, B Hardware, J Hill, C Hale, J Maxwell, E Roussou, A Adebajo
• Extended report: Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis (28 August, 2015)

  K L Winthrop, S-H Park, A Gul, M H Cardiel, J J Gomez-Reino, Y Tanaka, K Kwok, T Lukic, E Mortensen, D Ponce de Leon, R Riese, H Valdez
• Extended report: Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register (6 October, 2015)

  Jennifer H Humphreys, Marije K Verheul, Anne Barton, Alexander J MacGregor, Mark Lunt, Rene EM Toes, Deborah PM Symmons, Leendert A Trouw, Suzanne MM Verstappen
• Extended report: PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome (7 August, 2015)

  David F Fiorentino, Matthew Presby, Alan N Baer, Michelle Petri, Kerri E Rieger, Mark Soloski, Antony Rosen, Andrew L Mammen, Lisa Christopher-Stine, Livia Casciola-Rosen
• Extended report: Comparative efficacy of non-steroidal anti-inflammatory drugs in ankylosing spondylitis: a Bayesian network meta-analysis of clinical trials (6 August, 2015)

  Runsheng Wang, Abhijit Dasgupta, Michael M Ward
• Concise report: Assessment of fluorinated steroids to avert progression and mortality in anti-SSA/Ro-associated cardiac injury limited to the fetal conduction system (1 December, 2015)

  Peter M Izmirly, Amit Saxena, Sara K Sahl, Ummara Shah, Deborah M Friedman, Mimi Y Kim, Jill P Buyon
• Concise report: Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type (30 November, 2015)

  Sebastian Unizony, Miguel Villarreal, Eli M Miloslavsky, Na Lu, Peter A Merkel, Robert Spiera, Philip Seo, Carol A Langford, Gary S Hoffman, CG M Kallenberg, E William St. Clair, David Ikle, Nadia K Tchao, Linna Ding, Paul Brunetta, Hyon K Choi, Paul A Monach, Fernando Fervenza, John H Stone, Ulrich Specks