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BMJ Journals

Online First

April 23, 2024

Letter
No sign of elevated cardiovascular risk in patients with seropositive rheumatoid arthritis who remain on stable antirheumatic therapy: results from the nationwide Norwegian Cardio-Rheuma Register

Eirik Ikdahl, Anne Grete Semb, Anne M Kerola

doi: 10.1136/ard-2024-225758
Treatment
bDMARD can prevent the progression of AA amyloidosis to end-stage renal disease

Peter Kvacskay, Ute Hegenbart, Hanns-Martin Lorenz, Stefan O Schönland, Norbert Blank

doi: 10.1136/ard-2023-225114
Autoinflammatory disorders
Disease flares with baricitinib dose reductions and development of flare criteria in patients with CANDLE/PRAAS

Kader Cetin Gedik, Ana M Ortega-Villa, Grace Materne, Andre Rastegar, Gina A Montealegre Sanchez, Adam Reinhardt, Paul A Brogan, Yackov Berkun, Sara Murias, Maria Robles, Susanne Schalm, Adriana A de Jesus, Raphaela Goldbach-Mansky

doi: 10.1136/ard-2023-225463

April 22, 2024

Retraction
Retraction: PKCδ null mutations in a mouse model of osteoarthritis alter osteoarthritic pain independently of joint pathology by augmenting NGF/TrkA-induced axonal outgrowth
Free

doi: 10.1136/annrheumdis-2015-208444ret

April 18, 2024

Viewpoint
Potential and pitfalls of repurposing the CAR-T cell regimen for the treatment of autoimmune disease

Andrea R Daamen, Peter E Lipsky

doi: 10.1136/ard-2024-225638

April 12, 2024

Autoimmunity
Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events

Dionysis Nikolopoulos, Catherine Loukogiannaki, George Sentis, Panagiotis Garantziotis, Theodora Manolakou, Noemin Kapsala, Myrto Nikoloudaki, Antigone Pieta, Sofia Flouda, Ioannis Parodis, George Bertsias, Antonis Fanouriakis, Anastasia Filia, Dimitrios T Boumpas

doi: 10.1136/ard-2024-225664

April 09, 2024

Systemic sclerosis
Combined inhibition of IL-1, IL-33 and IL-36 signalling by targeting IL1RAP ameliorates skin and lung fibrosis in preclinical models of systemic sclerosis

Caitríona Grönberg, Sara Rattik, Cuong Tran-Manh, Xiang Zhou, Aleix Rius Rigau, Yi-Nan Li, Andrea-Hermina Györfi, Nicholas Dickel, Meik Kunz, Alexander Kreuter, Emil-Alexandru Matei, Honglin Zhu, Petter Skoog, David Liberg, Jörg HW Distler, Thuong Trinh-Minh

doi: 10.1136/ard-2023-225158
Spondyloarthritis
Risk of cardiovascular disease with high-dose versus low-dose use of non-steroidal anti-inflammatory drugs in ankylosing spondylitis

Ji-Won Kim, Jun Sik Yoon, Sojeong Park, Hasung Kim, Ji Sung Lee, Jung-Yoon Choe

doi: 10.1136/ard-2023-225406
Treatment
Janus kinase inhibitors and tumour necrosis factor inhibitors show a favourable safety profile and similar persistence in rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: real-world data from the BIOBADASER registry

Blanca Hernández-Cruz, Lucía Otero-Varela, Mercedes Freire-González, Noemí Busquets-Pérez, Alfredo Javier García González, Manuel Moreno-Ramos, Juan Maria Blanco-Madrigal, Sara Manrique-Arija, Eva Perez-Pampin, Dolores Ruiz-Montesino, Fernando Sánchez-Alonso, Carlos Sanchez-Piedra, Isabel Castrejón BIOBADASER Study Group

doi: 10.1136/ard-2023-225271

April 05, 2024

Correspondence response
Response to: Correspondence on ‘EULAR recommendations for the management of systemic lupus erythematosus: 2023 update’ by Fanouriakis et al
Free

Antonis Fanouriakis, Myrto Kostopoulou, George Bertsias, Dimitrios T Boumpas

doi: 10.1136/ard-2024-225617
Correspondence
Correspondence on ‘EULAR recommendations for the management of systemic lupus erythematosus: 2023 update’ by Fanouriakis et al
Free

Andreas Kronbichler, Hans-Joachim Anders, Eleni Frangou, Safak Mirioglu, Balazs Odler, Luis F Quintana, María José Soler Romeo, Annette Bruchfeld

doi: 10.1136/ard-2024-225563

April 04, 2024

Epidemiology
Development and evaluation of a text analytics algorithm for automated application of national COVID-19 shielding criteria in rheumatology patients

Meghna Jani, Ghada Alfattni, Maksim Belousov, Lynn Laidlaw, Yuanyuan Zhang, Michael Cheng, Karim Webb, Robyn Hamilton, Andrew S Kanter, William G Dixon, Goran Nenadic

doi: 10.1136/ard-2024-225544
Views on news
HLA-B27 and the role of specific T cell receptors in the pathogenesis of spondyloarthritis

Jürgen Braun, Elisabeth Märker-Hermann, Martin Rudwaleit, Joachim Sieper

doi: 10.1136/ard-2024-225661
Imaging
Validation and incorporation of digital entheses into a preliminary GLobal OMERACT Ultrasound DActylitis Score (GLOUDAS) in psoriatic arthritis

Esperanza Naredo, Maria Antonietta D'Agostino, Lene Terslev, Carlos Pineda, M Isabel Miguel, Joan Blasi, George A Bruyn, Marion C Kortekaas, Peter Mandl, Rodina Nestorova, Marcin Szkudlarek, Plamen Todorov, Violeta Vlad, Priscilla Wong, Catherine Bakewell, Emilio Filippucci, Alen Zabotti, Mihaela Micu, Florentin Vreju, Mohamed Mortada, José Alexandre Mendonça, Carlos A Guillen-Astete, Otto Olivas-Vergara, Annamaria Iagnocco, Petra Hanova, Ilaria Tinazzi, Peter V Balint, Sibel Zehra Aydin, David Kane, Helen Keen, Gurjit S Kaeley, Ingrid Möller

doi: 10.1136/ard-2023-225278

April 03, 2024

Correspondence response
Response to: Correspondence on ‘EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update’ by Hellmich et al
Free

Bernhard Hellmich, David Jayne

doi: 10.1136/ard-2024-225606
Systemic lupus erythematosus
Type I interferon blockade with anifrolumab in patients with systemic lupus erythematosus modulates key immunopathological pathways in a gene expression and proteomic analysis of two phase 3 trials

Tina Baker, Hoda Sharifian, Paul J Newcombe, Patrick G Gavin, Mark N Lazarus, Madhu Ramaswamy, Wendy I White, Nicola Ferrari, Daniel Muthas, Raj Tummala, Eric F Morand, Richard Furie, Edward M Vital, Chris Chamberlain, Adam Platt, Hussein Al-Mossawi, Philip Z Brohawn, Eszter Csomor

doi: 10.1136/ard-2023-225445

April 01, 2024

Rheumatoid arthritis
Altered serum metabolome as an indicator of paraneoplasia or concomitant cancer in patients with rheumatic disease

Karolina Gente, Manuel Feisst, Dorothea Marx, Karel D Klika, Petros Christopoulos, Jürgen Graf, Julia Will, Thomas Luft, Jessica C Hassel, Carsten Müller-Tidow, Rui A Carvalho, Hanns-Martin Lorenz, M Margarida Souto-Carneiro

doi: 10.1136/ard-2023-224839

March 29, 2024

Viewpoint
Should all patients with polymyalgia rheumatica have a vascular ultrasound assessment?

Sharon Cowley, Patricia Harkins, Colm Kirby, Richard Conway, David J Kane

doi: 10.1136/ard-2024-225650

March 28, 2024

Correspondence response
Response to: Correspondence on ‘Current myositis clinical trials and tribulations’ by Saygin et al
Free

Didem Saygin, Victoria Werth, Julie J Paik, Jin Kyun Park, Merrilee Needham, Ingrid E Lundberg, Lisa Christopher-Stine

doi: 10.1136/ard-2024-225762
Correspondence
Correspondence on ‘Current myositis clinical trials and tribulations’ by Saygin et al
Free

Sofia Ferreira Azevedo, Antonia Valenzuela, Cristian Alejandro Benitez, David A Isenberg, Elie Naddaf, Hector Chinoy, Jiří Vencovský, Latika Gupta, Liza McCann, Masataka Kuwana, Mazen M Dimachkie, Susan Shenoi, Lesley Ann Saketkoo, Pedro M Machado

doi: 10.1136/ard-2024-225751

March 26, 2024

Systemic lupus erythematosus
Characterisation of choroid plexus-infiltrating T cells reveals novel therapeutic targets in murine neuropsychiatric lupus

Erica Moore, Sushma Bharrhan, Deepak A Rao, Fernando Macian, Chaim Putterman

doi: 10.1136/ard-2023-224689
Letter
Gender equity in global rheumatology awards

Debaditya Roy, Laura Andreoli, Pavel V Ovseiko, Dzifa Dey, Yuva Ravindran, Shikha Singla, Ana María Arredondo González, Carlos Enrique Toro-Gutiérrez, Latika Gupta

doi: 10.1136/ard-2024-225670

March 25, 2024

Sjögren’s syndrome
Inhibition of JAK-STAT pathway corrects salivary gland inflammation and interferon driven immune activation in Sjögren’s disease

Sarthak Gupta, Eiko Yamada, Hiroyuki Nakamura, Paola Perez, Thomas JF Pranzatelli, Kalie Dominick, Shyh-Ing Jang, Mehdi Abed, Daniel Martin, Peter Burbelo, ChangYu Zheng, Ben French, Ilias Alevizos, Zohreh Khavandgar, Margaret Beach, Eileen Pelayo, Brian Walitt, Sarfaraz Hasni, Mariana J Kaplan, Mayank Tandon, Maria Teresa Magone, David E Kleiner, John A Chiorini, Alan Baer, Blake M Warner

doi: 10.1136/ard-2023-224842

March 20, 2024

Images in rheumatology
Fever, low back pain and skin ulcerations

Linrong He, Yongpeng Ge, Xiaoming Shu

doi: 10.1136/ard-2024-225662
Imaging
MRI-based synthetic CT: a new method for structural damage assessment in the spine in patients with axial spondyloarthritis – a comparison with low-dose CT and radiography

Simone Tromborg Willesen, Anna EF Hadsbjerg, Jakob Møllenbach Møller, Nora Vladimirova, Bimal M K Vora, Sengül Seven, Susanne Juhl Pedersen, Mikkel Østergaard

doi: 10.1136/ard-2023-225444

March 19, 2024

Psoriatic arthritis
Efficacy and safety of pharmacological treatment of psoriatic arthritis: a systematic literature research informing the 2023 update of the EULAR recommendations for the management of psoriatic arthritis

Andreas Kerschbaumer, Josef S Smolen, Ricardo J O Ferreira, Heidi Bertheussen, Xenofon Baraliakos, Daniel Aletaha, Dennis G McGonagle, Désirée van der Heijde, Iain B McInnes, Bente Appel Esbensen, Kevin L Winthrop, Wolf-Henning Boehncke, Jan W Schoones, Laure Gossec

doi: 10.1136/ard-2024-225534
Rheumatoid arthritis
Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery

Pang Lyu, Jinming Wen, Wenshuo Zhang, Ning Liu, Iris Stolzer, Andreas Gießl, Yewei Jia, Daniele Mauro, Fulin Zhang, Francesco Ciccia, Didier Soulat, Claudia Günther, Georg Schett, Aline Bozec

doi: 10.1136/ard-2023-224491

March 18, 2024

Recommendation
EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2023 update

Laure Gossec, Andreas Kerschbaumer, Ricardo J O Ferreira, Daniel Aletaha, Xenofon Baraliakos, Heidi Bertheussen, Wolf-Henning Boehncke, Bente Appel Esbensen, Iain B McInnes, Dennis McGonagle, Kevin L Winthrop, Andra Balanescu, Peter V Balint, Gerd R Burmester, Juan D Cañete, Pascal Claudepierre, Lihi Eder, Merete Lund Hetland, Annamaria Iagnocco, Lars Erik Kristensen, Rik Lories, Rubén Queiro, Daniele Mauro, Helena Marzo-Ortega, Philip J Mease, Peter Nash, Wendy Wagenaar, Laura Savage, Georg Schett, Stephanie J W Shoop-Worrall, Yoshiya Tanaka, Filip E Van den Bosch, Annette van der Helm-van Mil, Alen Zabotti, Désirée van der Heijde, Josef S Smolen

doi: 10.1136/ard-2024-225531

March 13, 2024

Osteoarthritis
Primary osteoarthritis chondrocyte map of chromatin conformation reveals novel candidate effector genes

Norbert Bittner, Chenfu Shi, Danyun Zhao, James Ding, Lorraine Southam, Diane Swift, Peter Kreitmaier, Mauro Tutino, Odysseas Stergiou, Jackson T S Cheung, Georgia Katsoula, Jenny Hankinson, Jeremy Mark Wilkinson, Gisela Orozco, Eleftheria Zeggini

doi: 10.1136/ard-2023-224945
Images in rheumatology
Clinical image: tophus in the sternoclavicular joint

Si Chen, Fengjing Liu, Jie Chen, Geng Gu, Haoyong Yu

doi: 10.1136/ard-2024-225609

March 05, 2024

Spondyloarthritis
Power Doppler signal at the enthesis and bone erosions are the most discriminative OMERACT ultrasound lesions for SpA: results from the DEUS (Defining Enthesitis on Ultrasound in Spondyloarthritis) multicentre study

Andrea Di Matteo, Gianluca Smerilli, Stefano Di Donato, An Ran Liu, Andrea Becciolini, Federica Camarda, Tomas Cazenave, Edoardo Cipolletta, Davide Corradini, Juan José de Agustín, Giulia Maria Destro Castaniti, Eleonora Di Donato, Luca Di Geso, Emine Duran, Bayram Farisogullari, Marco Fornaro, Francesca Francioso, Pamela Giorgis, Amelia Granel, Cristina Hernández-Díaz, Rudolf Horvath, Jana Hurnakova, Diogo Jesus, Omer Karadag, Ling Li, Josefina Marin, María Victoria Martire, Xabier Michelena, Erica Moscioni, Laura Muntean, Matteo Piga, Marcos Rosemffet, João Rovisco, Didem Sahin, Fausto Salaffi, Liliana Saraiva, Crescenzio Scioscia, Maria-Magdalena Tamas, Shun Tanimura, Aliki Venetsanopoulou, Lucio Ventura-Rios, Orlando Villota, Catalina Villota-Eraso, Paraskevi V Voulgari, Gentiana Vukatana, Johana Zacariaz Hereter, Helena Marzo-Ortega, Walter Grassi, Emilio Filippucci

doi: 10.1136/ard-2023-225443
Osteoarthritis
Global burden of early-onset osteoarthritis, 1990–2019: results from the Global Burden of Disease Study 2019

Qianlin Weng, Qiu Chen, Ting Jiang, Yuqing Zhang, Weiya Zhang, Michael Doherty, Junqing Xie, Ke Liu, Jiatian Li, Tuo Yang, Jie Wei, Guanghua Lei, Chao Zeng

doi: 10.1136/ard-2023-225324

March 02, 2024

Review
What rheumatologists need to know about mRNA vaccines: current status and future of mRNA vaccines in autoimmune inflammatory rheumatic diseases

Jin Kyun Park, Eun Bong Lee, Kevin L Winthrop

doi: 10.1136/ard-2024-225492
Systemic lupus erythematosus
Disease activity drives divergent epigenetic and transcriptomic reprogramming of monocyte subpopulations in systemic lupus erythematosus

Anna Guiomar Ferreté-Bonastre, Mónica Martínez-Gallo, Octavio Morante-Palacios, Celia Lourdes Calvillo, Josep Calafell-Segura, Javier Rodríguez-Ubreva, Manel Esteller, Josefina Cortés-Hernández, Esteban Ballestar

doi: 10.1136/ard-2023-225433

February 29, 2024

Systemic lupus erythematosus
Risk of flare and damage accrual after tapering glucocorticoids in modified serologically active clinically quiescent patients with systemic lupus erythematosus: a multinational observational cohort study

Yasuhiro Katsumata, Eisuke Inoue, Masayoshi Harigai, Jiacai Cho, Worawit Louthrenoo, Alberta Hoi, Vera Golder, Chak Sing Lau, Aisha Lateef, Yi-Hsing Chen, Shue-Fen Luo, Yeong-Jian Jan Wu, Laniyati Hamijoyo, Zhanguo Li, Sargunan Sockalingam, Sandra Navarra, Leonid Zamora, Yanjie Hao, Zhuoli Zhang, Madelynn Chan, Shereen Oon, Kristine Ng, Jun Kikuchi, Tsutomu Takeuchi, Fiona Goldblatt, Sean O’Neill, Nicola Tugnet, Annie Hui Nee Law, Sang-Cheol Bae, Yoshiya Tanaka, Naoaki Ohkubo, Sunil Kumar, Rangi Kandane-Rathnayake, Mandana Nikpour, Eric F Morand For the Asia-Pacific Lupus Collaboration

doi: 10.1136/ard-2023-225369
Spondyloarthritis
Sacroiliac radiographic progression over 10 years in axSpA: data from the DESIR inception cohort

Anna Molto, Clementina López-Medina, Alexandre Sepriano, Sofia Ramiro, Manouk de Hooge, Miranda van Lunteren, Victoria Navarro-Compán, Daniel Wendling, Maxime Dougados

doi: 10.1136/ard-2023-225184
Myositis
Novel endotypes of antisynthetase syndrome identified independent of anti-aminoacyl transfer RNA synthetase antibody specificity that improve prognostic stratification

Shiyu Wu, Xinyue Xiao, Yingfang Zhang, Xinxin Zhang, Guochun Wang, Qinglin Peng

doi: 10.1136/ard-2023-225284

February 28, 2024

Epidemiology
Changes in alcohol intake and serum urate changes: longitudinal analyses of annual medical examination database

Sho Fukui, Masato Okada, Tomohiro Shinozaki, Takahiro Asano, Takehiro Nakai, Hiromichi Tamaki, Mitsumasa Kishimoto, Hiroshi Hasegawa, Takeaki Matsuda, Javier Marrugo, Sara K Tedeschi, Hyon Choi, Daniel H Solomon

doi: 10.1136/ard-2023-225389
Editorial
Referral of patients with suspected polymyalgia rheumatica: how complete is our view of ‘planet PMR?’
Free

Dario Camellino, Eric L Matteson

doi: 10.1136/ard-2023-225217
Crystal arthropathies
Systemic inflammatory cytokine profiles in patients with gout during flare, intercritical and treat-to-target phases: TNFSF14 as new biomarker

Hang-Korng Ea, Brenda Kischkel, Twinu Wilson Chirayath, Viola Klück, Caroline Aparicio, Hoang-Uyen Loeung, Philippe Manivet, Tim Jansen, Mylène Zarka, Frédéric Lioté, Augustin Latourte, Thomas Bardin, Alan Gauffenic, Eric Vicaut, Tania Octavia Crișan, Mihai G Netea, Pascal Richette, Leo AB Joosten

doi: 10.1136/ard-2023-225305
Recommendation
Recommendations for early referral of individuals with suspected polymyalgia rheumatica: an initiative from the international giant cell arteritis and polymyalgia rheumatica study group

Kresten Krarup Keller, Chetan B Mukhtyar, Andreas Wiggers Nielsen, Andrea Katharina Hemmig, Sarah Louise Mackie, Sebastian Eduardo Sattui, Ellen-Margrethe Hauge, Anisha Dua, Toby Helliwell, Lorna Neill, Daniel Blockmans, Valérie Devauchelle-Pensec, Eric Hayes, Annett Jansen Venneboer, Sara Monti, Cristina Ponte, Eugenio De Miguel, Mark Matza, Kenneth J Warrington, Kevin Byram, Kinanah Yaseen, Christine Peoples, Michael Putman, Lindsay Lally, Michael Finikiotis, Simone Appenzeller, Ugo Caramori, Carlos Enrique Toro-Gutiérrez, Elisabeth Backhouse, María Camila Guerrero Oviedo, Victor Román Pimentel-Quiroz, Helen Isobel Keen, Claire Elizabeth Owen, Thomas Daikeler, Annette de Thurah, Wolfgang A Schmidt, Elisabeth Brouwer, Christian Dejaco

doi: 10.1136/ard-2023-225134
Letter
Acute rheumatic fever in the province of Manitoba, Canada, before and after the coronavirus (COVID-19) pandemic

Kayla Edison, Dion Pepelassis, Reeni Soni, Daryl Schantz, Ilan Buffo

doi: 10.1136/ard-2023-225294
Systemic lupus erythematosus
KLF2 enhancer variant rs4808485 increases lupus risk by modulating inflammasome machinery and cellular homoeostasis

Manish Kumar Singh, Harikrishna Reddy Rallabandi, Xu-Jie Zhou, Yuan-Yuan Qi, Zhan-Zheng Zhao, Ting Gan, Hong Zhang, Loren L Looger, Swapan K Nath

doi: 10.1136/ard-2023-224953
Letter
Focal adhesion protein Lasp1 links the Arp2/3 complex to adherens junctions and promotes motility of arthritic fibroblast-like synoviocytes

Denise Beckmann, Annika Krause, Uwe Hansen, Hans P Kiener, Thomas Karonitsch, Stephan Blüml, Joachim Kremerskothen, Hermann Pavenstädt, Thomas Pap, Adelheid Korb-Pap

doi: 10.1136/ard-2023-225241
Review
Immune response to post-translationally modified proteins in rheumatoid arthritis: what makes it special?

Diane van der Woude, René E M Toes

doi: 10.1136/ard-2023-224103
Systemic lupus erythematosus
Molecular characterisation of lupus low disease activity state (LLDAS) and DORIS remission by whole-blood transcriptome-based pathways in a pan-European systemic lupus erythematosus cohort

Ioannis Parodis, Julius Lindblom, Guillermo Barturen, Rafaela Ortega-Castro, Ricard Cervera, Jacques-Olivier Pers, Fernanda Genre, Falk Hiepe, Maria Gerosa, László Kovács, Ellen De Langhe, Silvia Piantoni, Georg Stummvoll, Carlos Vasconcelos, Barbara Vigone, Torsten Witte, PRECISESADS Clinical Consortium, Marta E Alarcón-Riquelme, Lorenzo Beretta

doi: 10.1136/ard-2023-224795

February 26, 2024

Autoinflammatory disorders
Interrupting an IFN-γ-dependent feedback loop in the syndrome of pyogenic arthritis with pyoderma gangrenosum and acne

Wonyong Lee, Deborah L Stone, Patrycja Hoffmann, Sofia Rosenzweig, Wanxia Li Tsai, Massimo Gadina, Tina Romeo, Chyi-Chia Richard Lee, Davide Randazzo, Pallavi Pimpale Chavan, Kalpana Manthiram, Scott Canna, Yong Hwan Park, Amanda K Ombrello, Ivona Aksentijevich, Daniel L Kastner, Jae Jin Chae

doi: 10.1136/ard-2023-225085

February 22, 2024

Osteoarthritis
Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration

Yue Fan, Xuzhao Bian, Xiaogao Meng, Lei Li, Laiyi Fu, Yanan Zhang, Long Wang, Yan Zhang, Dalong Gao, Xiong Guo, Mikko Juhani Lammi, Guangdun Peng, Shiquan Sun

doi: 10.1136/ard-2023-224420
Correspondence
Correspondence on ‘EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update’ by Hellmich et al
Free

Joanna C Robson, Montserrat M Díaz Encarnación, Peter Verhoeven, Raquel Olivenza Antón, Monica Balcells-Oliver, Tamara Popov, Sara Monti, Andreas Kronbichler

doi: 10.1136/ard-2024-225583

February 14, 2024

Review
Annals of the Rheumatic Diseases collection on pregnancy 2018–2023: observational data-driven knowledge

Kate Duhig, Kimme L Hyrich

doi: 10.1136/ard-2023-224861

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