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Correlation of serum level of high mobility group box 1 with the burden of granulomatous inflammation in granulomatosis with polyangiitis (Wegener's)
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- Published on: 13 April 2016
- Published on: 13 April 2016HMGB-1 in ANCA-associated vasculitis (AAV):correlation with disease manifestationsShow More
Dear editor,
Recently Henes et al reported that serum levels of the proinflammatory mediator high mobility group box-1 protein (HMGB1) were elevated and showed a significant correlation with the burden of granulomatous inflammation in patients with Granulomatosis with polyangiitis (GPA or Wegener) (1). The same group has previously published data suggesting that HMGB1 is a marker of GPA and that HMGB1 is not detec...
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